Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793944 | 0.85 | SMN1; SMN2 (0.49) | TSHRSMN1; SMN2ALDH1A1MAPTNPSR1 | |
| SCHEMBL5794078 | 0.83 | MAPT (0.46) | SMN1; SMN2HPGDALDH1A1MAPTKMT2A | |
| SCHEMBL4154993 | 0.80 | TSHR (0.46) | TSHRSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL4154987 | 0.80 | TSHR (0.46) | TSHRSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL4154989 | 0.80 | TSHR (0.46) | TSHRSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL24501487 | 0.80 | TSHR (0.46) | TSHRSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL29830598 | 0.80 | TSHR (0.46) | TSHRSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL29830745 | 0.80 | TSHR (0.46) | TSHRSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL31749569 | 0.79 | TSHR (0.45) | TSHRSMN1; SMN2HPGDMAPTMAPK1 | |
| SCHEMBL7071171 | 0.79 | MAPT (0.46) | TSHRSMN1; SMN2HPGDMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006013399-A1 | PHARMACEUTICAL INTERMEDIATES AND A PROCESS FOR THE PREPARATION THEREOF | EGIS Gyógyszergyár Rt. (HU) | 2006-02-09 | — | — | WO | claimed |
| WO-2006013399-A1 | PHARMACEUTICAL INTERMEDIATES AND A PROCESS FOR THE PREPARATION THEREOF | EGIS Gyógyszergyár Rt. (HU) | 2006-02-09 | — | — | WO | disclosed |