Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501377 | 0.84 | ELANE (0.42) | MAPTGAATRPV1HPGDKMT2A | |
| SCHEMBL5094293 | 0.84 | MAPT (0.49) | MAPTGAATRPV1KMT2AMEN1 | |
| SCHEMBL5094297 | 0.84 | MAPT (0.49) | MAPTGAATRPV1KMT2AMEN1 | |
| SCHEMBL5793944 | 0.83 | SMN1; SMN2 (0.49) | MAPTGAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9726821 | 0.83 | MAPT (0.47) | MAPTGAAKMT2AMEN1LMNA | |
| SCHEMBL5796665 | 0.83 | TSHR (0.47) | MAPTHPGDKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12596917 | 0.81 | LMNA (0.45) | MAPTGAATRPV1HPGDKMT2A | |
| SCHEMBL31749890 | 0.80 | PARP1 (0.50) | MAPTGAATRPV1HPGDKMT2A | |
| SCHEMBL7682829 | 0.80 | PARP1 (0.50) | MAPTGAATRPV1HPGDKMT2A | |
| SCHEMBL7682832 | 0.80 | PARP1 (0.50) | MAPTGAATRPV1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006013399-A1 | PHARMACEUTICAL INTERMEDIATES AND A PROCESS FOR THE PREPARATION THEREOF | EGIS Gyógyszergyár Rt. (HU) | 2006-02-09 | — | — | WO | disclosed |