Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623291 | 0.97 | CALM1 (0.41) | CALM1GBA1NOS1NOS2TSHR | |
| SCHEMBL4357593 | 0.87 | CALM1 (0.45) | CALM1GBA1TSHRIDO1TP53 | |
| SCHEMBL6002826 | 0.85 | CALM1 (0.39) | CALM1GBA1TSHRIDO1TP53 | |
| SCHEMBL4361398 | 0.76 | GBA1 (0.41) | CALM1GBA1NOS1NOS2POLB | |
| SCHEMBL29844018 | 0.72 | — | — | |
| SCHEMBL27437866 | 0.71 | ALDH1A1 (0.42) | LOXL2ALDH1A1 | |
| SCHEMBL30075933 | 0.70 | — | — | |
| SCHEMBL545248 | 0.69 | TSHR (0.56) | TSHRIDO1POLB | |
| SCHEMBL10321041 | 0.69 | GBA1 (0.47) | GBA1NOS1NOS2 | |
| SCHEMBL27275720 | 0.69 | ALDH1A1 (0.39) | LOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006045886-A1 | CONTINUOUS PROCESS FOR OBTAINING A PRODUCT COMPRISING AT LEAST ONE HYDROGEN ISOTOPE | HARTONEN KARI (FI) | 2006-05-04 | — | — | WO | disclosed |
| US-20030113805-A1 | Intrinsically labelled solid support | ZENECA LIMITED, A LONDON CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-20010007740-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LTD. | 2001-07-12 | — | — | US | disclosed |
| EP-0843656-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LIMITED (GB) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997003931-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |