Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.82 |
| ▸ | CNR1 | P21554 | 7/20 | 0.82 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367406 | 0.90 | CNR2 (1.00) | CNR2CNR1RAB9ANPC1MEN1 | |
| SCHEMBL5794343 | 0.89 | CNR1 (0.65) | CNR2CNR1RAB9ANPC1MEN1 | |
| SCHEMBL5793966 | 0.86 | CNR2 (0.61) | CNR2CNR1RAB9ANPC1KMT2A | |
| SCHEMBL15506185 | 0.84 | ALDH1A1 (0.68) | CNR2CNR1MEN1KMT2AMAPT | |
| SCHEMBL5625769 | 0.83 | MAPK1 (0.61) | CNR2CNR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5623000 | 0.81 | CNR2 (1.00) | CNR2CNR1RAB9ANPC1MAPT | |
| SCHEMBL5626636 | 0.79 | CNR2 (1.00) | CNR2CNR1RAB9ANPC1MAPT | |
| SCHEMBL5623445 | 0.79 | CNR2 (1.00) | CNR2CNR1RAB9ANPC1MEN1 | |
| SCHEMBL5623834 | 0.78 | CNR2 (0.78) | CNR2CNR1RAB9ANPC1MEN1 | |
| SCHEMBL29717171 | 0.77 | CNR2 (0.73) | CNR2CNR1RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006044645-A2 | SULFAMOYL BENZAMIDES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2006-04-27 | — | — | WO | claimed |
| WO-2006044645-A2 | SULFAMOYL BENZAMIDES AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2006-04-27 | — | — | WO | disclosed |