Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 17/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793470 | 1.00 | XIAP (0.43) | XIAPTAAR1KIF11KCNH2 | |
| SCHEMBL5794434 | 0.83 | KDM1A (0.44) | KIF11KCNH2 | |
| SCHEMBL5793469 | 0.83 | KDM1A (0.44) | KIF11KCNH2 | |
| SCHEMBL4843496 | 0.79 | PSEN1 (0.49) | — | |
| SCHEMBL4833355 | 0.79 | PSEN1 (0.49) | — | |
| SCHEMBL4841673 | 0.79 | PSEN1 (0.49) | — | |
| SCHEMBL4834200 | 0.79 | PSEN1 (0.49) | — | |
| SCHEMBL5793583 | 0.79 | XIAP (0.47) | XIAPTAAR1KCNH2 | |
| SCHEMBL5791890 | 0.79 | XIAP (0.43) | XIAPTAAR1 | |
| SCHEMBL4841305 | 0.78 | PSEN1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | claimed |
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |