Ethylene Glycol

Ethylene Glycol

SCHEMBL5794445

C=COCc1ccccc1.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
TDP1 Q9NUW8 2/20 0.43
IDO1 P14902 1/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
LTA4H P09960 1/20 0.41
EPHX2 P34913 1/20 0.41
AGXT P21549 1/20 0.40
ALDH1A1 P00352 3/20 0.39
LMNA P02545 3/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 2/20 0.39
CYP1A2 P05177 1/20 0.39
PTGS1 P23219 1/20 0.39
CYP2C19 P33261 1/20 0.39
PTGS2 P35354 1/20 0.39
HIF1A Q16665 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145091 0.91 TSHR (0.52) TSHRTDP1IDO1AGXTALDH1A1
Water SCHEMBL28226317 0.89 TSHR (0.50) TSHRTDP1IDO1AGXTALDH1A1
Phosphine SCHEMBL28323888 0.89 TSHR (0.50) TSHRTDP1IDO1AGXTALDH1A1
Ethylene SCHEMBL28940632 0.89 TSHR (0.50) TSHRTDP1IDO1AGXTALDH1A1
Phenol SCHEMBL27969359 0.88 LMNA (0.48) TSHRTDP1IDO1AGXTALDH1A1
Ethane SCHEMBL28154494 0.87 TSHR (0.48) TSHRTDP1IDO1AGXTALDH1A1
Propane SCHEMBL28154497 0.85 TSHR (0.46) TSHRTDP1IDO1AGXTALDH1A1
SCHEMBL29286335 0.82 TSHR (0.43) TSHRIDO1AGXTALDH1A1LMNA
Styrene SCHEMBL11234469 0.82 ALDH1A1 (0.56) TSHRIDO1AGXTALDH1A1LMNA
SCHEMBL16243987 0.80 TSHR (0.41) TSHRIDO1AGXTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006028252-A1 COPOLYMER AND DISPERSANT NIPPON SHOKUBAI CO., LTD. (JP) 2006-03-16 WO disclosed