SCHEMBL5794639

SCHEMBL5794639

CC(CNS(=O)(=O)C(C)C)c1ccc(-c2ccccc2C#N)cc1

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 19/20 0.67
GRIA2 P42262 2/20 0.67
GRIA1 P42261 1/20 0.67
GRIA3 P42263 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5877884 0.82 GRIA4 (0.74) GRIA4GRIA2GRIA1GRIA3
SCHEMBL8164711 0.81 GRIA4 (0.67) GRIA4GRIA2GRIA1GRIA3
SCHEMBL3828607 0.81 GRIA4 (0.67) GRIA4GRIA2GRIA1GRIA3
SCHEMBL5877848 0.81 GRIA4 (0.72) GRIA4GRIA2GRIA1GRIA3
SCHEMBL32681164 0.81 GRIA4 (1.00) GRIA4GRIA2GRIA1GRIA3
SCHEMBL5878098 0.81 GRIA4 (1.00) GRIA4GRIA2GRIA1GRIA3
SCHEMBL2134262 0.80 GRIA4 (1.00) GRIA4GRIA2GRIA1GRIA3
SCHEMBL959005 0.80 GRIA4 (1.00) GRIA4GRIA2GRIA1GRIA3
SCHEMBL5878433 0.80 GRIA4 (1.00) GRIA4GRIA2GRIA1GRIA3
SCHEMBL5877625 0.80 GRIA4 (0.70) GRIA4GRIA2GRIA1GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006034196-A1 COMPOSITIONS FOR ENHANCING MEMORY AND METHODS THEREFOR LIFELIKE BIOMATIC INC. (US) 2006-03-30 WO claimed
US-20060063707-A1 Compositions for enhancing memory and methods therefor LIFELIKE BIOMATIC, INC. (US) 2006-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063707-A1 Compositions for enhancing memory and methods therefor GRIN1, GRIN3A, GRIN2A GRIA4 19/4885GRIA2 25/4885GRIA1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.