Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793542 | 0.86 | CACNA1F (0.33) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL7093009 | 0.84 | CACNA1F (0.33) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6673258 | 0.83 | EPHX2 (0.36) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL7093638 | 0.82 | KCNH2 (0.39) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6668181 | 0.81 | CACNA1F (0.33) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6673571 | 0.81 | ALDH1A1 (0.32) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6669775 | 0.81 | KCNH2 (0.33) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL7097498 | 0.81 | MEN1 (0.35) | KCNH2 | |
| SCHEMBL7092989 | 0.80 | CACNA1F (0.31) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL6669192 | 0.80 | KCNH2 (0.33) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667994-A1 | QUINOLONE ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026154-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |