Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564437 | 0.78 | ELANE (0.39) | ELANEDYRK1A | |
| SCHEMBL5793353 | 0.78 | CHEK1 (0.50) | ELANECCNCCDK8 | |
| SCHEMBL4966850 | 0.78 | PARP1 (0.50) | PARP1ELANETYMS | |
| SCHEMBL28418624 | 0.78 | PARP1 (0.50) | PARP1ELANETYMSC1R | |
| SCHEMBL28419509 | 0.78 | ELANE (0.54) | PARP1ELANEC1R | |
| SCHEMBL11207150 | 0.78 | ELANE (0.42) | ELANEDYRK1A | |
| SCHEMBL10781415 | 0.76 | ELANE (0.41) | ELANEDYRK1A | |
| SCHEMBL28249291 | 0.75 | KDM4E (0.42) | ELANEDYRK1A | |
| SCHEMBL17190724 | 0.74 | LMNA (0.48) | C1R | |
| SCHEMBL912750 | 0.72 | ELANE (0.52) | PARP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |