SCHEMBL11207150

SCHEMBL11207150

O=c1ocnc2cc3c(=O)ocnc3cc12

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.42
KCNA3 P22001 1/20 0.34
DYRK1A Q13627 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10781415 0.93 ELANE (0.41) ELANEKCNA3DYRK1AMEN1ALDH1A1
SCHEMBL6260526 0.82 ELANE (0.53) ELANEKCNA3MEN1ALDH1A1GAA
SCHEMBL23159972 0.80 CTSG (0.43) ALDH1A1GAA
SCHEMBL13090427 0.79 ELANE (0.44) ELANEKCNA3MEN1ALDH1A1GAA
SCHEMBL5793353 0.78 CHEK1 (0.50) ELANEMEN1ALDH1A1GAAKMT2A
SCHEMBL4966850 0.78 PARP1 (0.50) ELANEMEN1ALDH1A1GAAKMT2A
SCHEMBL13564437 0.78 ELANE (0.39) ELANEDYRK1A
SCHEMBL9507959 0.78 ELANE (0.48) ELANEDYRK1AMEN1ALDH1A1GAA
SCHEMBL5795085 0.78 PARP1 (0.50) ELANEDYRK1A
SCHEMBL922667 0.75 ELANE (0.39) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0020944-B1 PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING AN INCREASED DEGREE OF POLYMERISATION, THESE AROMATIC POLYESTERS, PROCESS FOR PRODUCING MOLDED ARTICLES COMPOSED THEREOF, AND THESE MOLDED ARTICLES TEIJIN LIMITED (JP) 1983-07-27 EP disclosed
US-4331800-A CHAIN EXTENSION WITH A BIS/CYCLIC IMINOETHER TEIJIN LIMITED (JP) 1982-05-25 US disclosed
EP-0020944-A1 Process for producing aromatic polyesters having an increased degree of polymerisation, these aromatic polyesters, process for producing molded articles composed thereof, and these molded articles TEIJIN LIMITED (JP) 1981-01-07 EP disclosed