Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762669 | 0.87 | SLC2A1 (0.35) | BRD4SLC6A2SLC2A1C5AR1 | |
| SCHEMBL1762995 | 0.82 | DHFR (0.33) | C5AR1 | |
| SCHEMBL1763005 | 0.81 | MEN1 (0.37) | BRD4C5AR1 | |
| SCHEMBL1762713 | 0.73 | DGAT1 (0.42) | C5AR1 | |
| SCHEMBL1762617 | 0.73 | C5AR1 (0.38) | C5AR1 | |
| SCHEMBL1762893 | 0.72 | PTK2 (0.39) | — | |
| SCHEMBL5796068 | 0.72 | TLR8 (0.40) | — | |
| SCHEMBL1762637 | 0.72 | C5AR1 (0.37) | C5AR1 | |
| SCHEMBL1762602 | 0.72 | C5AR1 (0.37) | C5AR1 | |
| SCHEMBL1762746 | 0.71 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006042102-A2 | PYRROLO-PYRIDINE, PYRROLO-PYRIMIDINE AND RELATED HETEROCYCLIC COMPOUNDS | NEUROGEN CORPORATION (US) | 2006-04-20 | — | — | WO | disclosed |