Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | NHERF1 | O14745 | 3/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174359 | 0.82 | KDM4E (0.72) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL832227 | 0.81 | RAB9A (0.67) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4666737 | 0.80 | F7 (0.60) | RAB9ANPC1HRH3PYGLPDGFRB | |
| SCHEMBL7493127 | 0.80 | FLT3 (0.57) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3494717 | 0.80 | HRH4 (0.51) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6049346 | 0.79 | SRC (0.47) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29496122 | 0.78 | KDM4E (0.63) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL318243 | 0.78 | KDM4E (0.63) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23486667 | 0.78 | MMP13 (0.51) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3246114 | 0.78 | HRH3 (0.51) | KDM4ERAB9AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034480-A2 | SULFONAMIDE BICYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-03-30 | — | — | WO | disclosed |