Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 3/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.53 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.53 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226043 | 1.00 | AQP1 (0.56) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4226179 | 0.90 | AQP1 (0.70) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4225459 | 0.88 | AQP1 (0.52) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14112673 | 0.87 | AQP1 (0.46) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8211425 | 0.87 | AQP1 (0.46) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4226753 | 0.86 | AQP1 (0.65) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4219184 | 0.86 | PRKAB2 (0.54) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL5794284 | 0.86 | PRKAB2 (0.54) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL5794592 | 0.86 | PRKAB2 (0.54) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| Hydrochloric Acid SCHEMBL4621208 | 0.86 | AQP1 (0.45) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000902-A1 | DIHYDROBENZOFURAN COMPOUNDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2006-01-05 | — | — | WO | disclosed |