Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752563 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2L3MBTL1KDM4ELMNATDP1 | |
| SCHEMBL5133848 | 0.74 | KEAP1 (0.52) | TDP1TP53ALDH1A1GAAKMT2A | |
| SCHEMBL14050964 | 0.74 | MEN1 (0.48) | SMN1; SMN2L3MBTL1KDM4ELMNAHTT | |
| SCHEMBL6745096 | 0.74 | KDM4E (0.50) | SMN1; SMN2L3MBTL1KDM4ELMNATDP1 | |
| SCHEMBL5795507 | 0.73 | KDM4E (0.52) | TRPM8SMN1; SMN2L3MBTL1KDM4ELMNA | |
| SCHEMBL7425804 | 0.73 | KDM4E (0.53) | SMN1; SMN2L3MBTL1KDM4ELMNATDP1 | |
| SCHEMBL28931079 | 0.73 | KDM4E (0.48) | SMN1; SMN2L3MBTL1KDM4ELMNATDP1 | |
| SCHEMBL4974076 | 0.73 | KDM4E (0.48) | SMN1; SMN2L3MBTL1KDM4ELMNATDP1 | |
| SCHEMBL3714318 | 0.73 | KDM4E (0.48) | SMN1; SMN2L3MBTL1KDM4ELMNATDP1 | |
| SCHEMBL5462166 | 0.72 | SMN1; SMN2 (0.55) | TRPM8SMN1; SMN2L3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006018544-A1 | COMPOSITION CONTAINING A THIOPHENIC OR BENZOTHIOPHENIC COMPOUND AND EXHIBITING A PUMP NORA INHIBITING ACTIVITY | UNIVERSITE CLAUDE BERNARD LYON I (FR) | 2006-02-23 | — | — | WO | claimed |
| WO-2006018544-A1 | COMPOSITION CONTAINING A THIOPHENIC OR BENZOTHIOPHENIC COMPOUND AND EXHIBITING A PUMP NORA INHIBITING ACTIVITY | UNIVERSITE CLAUDE BERNARD LYON I (FR) | 2006-02-23 | — | — | WO | disclosed |