Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582217 | 0.73 | KDM4E (0.30) | L3MBTL1 | |
| SCHEMBL5695315 | 0.73 | — | — | |
| SCHEMBL22496022 | 0.72 | — | — | |
| Bicarbonate SCHEMBL5795371 | 0.72 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL11809142 | 0.72 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL2696185 | 0.71 | CYP3A4 (0.31) | MEN1CYP3A4KMT2A | |
| SCHEMBL25369782 | 0.70 | GABRA1 (0.39) | MEN1CYP3A4KMT2ATDP1L3MBTL1 | |
| SCHEMBL31618516 | 0.68 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL2699373 | 0.66 | — | — | |
| SCHEMBL7729587 | 0.66 | XDH (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006019673-A2 | JIADIFENIN ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2006-02-23 | — | — | WO | disclosed |