Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24088568 | 0.85 | CYP19A1 (0.47) | CYP19A1P2RX4SRCKDM4EMEN1 | |
| SCHEMBL3022170 | 0.85 | CYP19A1 (0.60) | CYP19A1P2RX4SRCKDM4EMEN1 | |
| SCHEMBL30007452 | 0.82 | CYP19A1 (1.00) | CYP19A1P2RX4SRCKDM4EMEN1 | |
| SCHEMBL151053 | 0.82 | CYP19A1 (1.00) | CYP19A1P2RX4SRCKDM4EMEN1 | |
| SCHEMBL4849333 | 0.82 | KDM4E (0.67) | KDM4EMEN1KMT2ASMN1; SMN2MAPT | |
| Bromide SCHEMBL28888744 | 0.80 | CYP19A1 (0.95) | CYP19A1P2RX4SRCKDM4EMEN1 | |
| Ammonia Solution, Strong SCHEMBL29210102 | 0.80 | CYP19A1 (0.95) | CYP19A1P2RX4SRCKDM4EMEN1 | |
| SCHEMBL9398256 | 0.80 | CYP19A1 (0.95) | CYP19A1P2RX4SRCKDM4EMEN1 | |
| SCHEMBL13957035 | 0.80 | CYP19A1 (0.86) | CYP19A1P2RX4HDAC6HDAC1HDAC10 | |
| SCHEMBL17251490 | 0.80 | CYP19A1 (0.62) | CYP19A1P2RX4SRCKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090066238-A1 | Electroluminescent materials grafted with charge transport moieties having graded ionization potential or electrophilic property and their application in light-emitting diodes | NATIONAL TSING HUA UNIVERSITY (TW) | 2009-03-12 | — | — | US | disclosed |
| US-20090066238-A1 | Electroluminescent materials grafted with charge transport moieties having graded ionization potential or electrophilic property and their application in light-emitting diodes | NATIONAL TSING HUA UNIVERSITY (TW) | 2009-03-12 | — | — | US | disclosed |
| WO-2006012310-A2 | CARBAZOLE DERIVATIVES FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |