Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799824 | 1.00 | HDAC1 (0.47) | HDAC1PARP14HDAC3HDAC6HDAC2 | |
| SCHEMBL5797058 | 0.92 | PARP14 (0.43) | HDAC1PARP14MAPTMEN1KMT2A | |
| SCHEMBL5798774 | 0.92 | PARP14 (0.43) | HDAC1PARP14MAPTMEN1KMT2A | |
| SCHEMBL5799276 | 0.90 | HDAC1 (0.49) | HDAC1PARP14HDAC3HDAC6HDAC2 | |
| SCHEMBL5799274 | 0.90 | HDAC1 (0.49) | HDAC1PARP14HDAC3HDAC6HDAC2 | |
| SCHEMBL5795517 | 0.90 | P2RX3 (0.42) | HDAC1PARP14HDAC3HDAC6HDAC2 | |
| SCHEMBL5795513 | 0.90 | P2RX3 (0.42) | HDAC1PARP14HDAC3HDAC6HDAC2 | |
| SCHEMBL5796106 | 0.85 | P2RX3 (0.43) | HDAC1PARP14HDAC3HDAC6HDAC2 | |
| SCHEMBL5798858 | 0.84 | P2RX3 (0.47) | HDAC1PARP14HDAC3HDAC6HDAC2 | |
| SCHEMBL5796184 | 0.83 | HDAC6 (0.51) | HDAC1HDAC3HDAC6HDAC2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | claimed |
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |