SCHEMBL5795486

SCHEMBL5795486

NC(=O)[C@H]1CN(c2ccc(C3CCSC(=O)C3)cc2)C(=O)O1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.47
F10 P00742 7/20 0.38
FADS1 O60427 1/20 0.33
ATM Q13315 1/20 0.32
F2 P00734 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3045229 0.85 MAOA (0.51) MAOAF10FADS1
SCHEMBL5795229 0.83 MAOA (0.69) MAOAF10
SCHEMBL6617609 0.83 MAOA (0.47) MAOAF10FADS1F2
SCHEMBL5792952 0.81 MAOA (0.53) MAOAF10
SCHEMBL7849117 0.78 MAOA (0.55) MAOAF10F2
SCHEMBL5792883 0.77 MAOA (0.46) MAOAF10FADS1
SCHEMBL5792480 0.77 MAOA (0.46) MAOAF10FADS1
SCHEMBL13515448 0.77 MAOA (0.50) MAOAF10FADS1
SCHEMBL4882488 0.76 MAOA (0.48) MAOAF10FADS1
SCHEMBL3044472 0.76 MAOA (0.49) MAOAF10FADS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1478629-B1 N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS PHARMACIA & UPJOHN CO LLC (US) 2006-10-11 EP claimed