Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841082 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL4841551 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL4843406 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL14254617 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL5792149 | 0.80 | MEN1 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPTRECQL | |
| SCHEMBL4845496 | 0.80 | MEN1 (0.36) | ALDH1A1SMN1; SMN2LMNAMAPTRECQL | |
| SCHEMBL5791105 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL4839870 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL4843507 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL4841214 | 0.78 | TSHR (0.38) | ALDH1A1LMNAMAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |