Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797343 | 0.90 | MAPT (0.50) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL5798805 | 0.88 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL5810378 | 0.86 | MAPT (0.46) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL5808810 | 0.86 | MAPT (0.54) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL5797097 | 0.84 | NPC1 (0.46) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL5799655 | 0.81 | RAB9A (0.51) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL5796789 | 0.77 | MAPT (0.58) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1306405 | 0.77 | ALDH1A1 (0.47) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL5824078 | 0.77 | MAPT (0.44) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL1306406 | 0.77 | ALDH1A1 (0.47) | MAPTRAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |