Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796327 | 0.93 | P2RX3 (0.54) | P2RX3PPARGPPARDPPARAMAPT | |
| SCHEMBL5796329 | 0.93 | P2RX3 (0.54) | P2RX3PPARGPPARDPPARAMAPT | |
| SCHEMBL5819819 | 0.93 | P2RX3 (0.43) | P2RX3PPARGPPARDPPARAMAPT | |
| SCHEMBL5797822 | 0.82 | MEN1 (0.46) | P2RX3MAPTKDM4EALDH1A1DAPK1 | |
| SCHEMBL5796791 | 0.78 | P2RX3 (0.47) | P2RX3MAPTKDM4EALDH1A1DAPK1 | |
| SCHEMBL5813652 | 0.78 | MEN1 (0.50) | P2RX3MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL5799773 | 0.75 | P2RX3 (0.43) | P2RX3MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL5799769 | 0.75 | P2RX3 (0.43) | P2RX3MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL5799787 | 0.75 | HDAC3 (0.56) | P2RX3MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL5799788 | 0.75 | HDAC3 (0.56) | P2RX3MAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |