Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799769 | 1.00 | P2RX3 (0.43) | P2RX3ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5797822 | 0.93 | MEN1 (0.46) | P2RX3ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5796297 | 0.92 | P2RX3 (0.52) | P2RX3ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5809911 | 0.89 | HPGD (0.44) | P2RX3ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5809908 | 0.89 | HPGD (0.44) | P2RX3ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5796119 | 0.88 | MAPT (0.47) | P2RX3ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5810269 | 0.86 | ALDH1A1 (0.43) | P2RX3ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5810275 | 0.86 | ALDH1A1 (0.43) | P2RX3ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL5819819 | 0.84 | P2RX3 (0.43) | P2RX3ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL5814020 | 0.83 | ALPL (0.45) | P2RX3ALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |