Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799654 | 0.91 | NPC1 (0.39) | NPC1RAB9AMEN1KMT2ARGS12 | |
| SCHEMBL5799059 | 0.89 | NPC1 (0.39) | NPC1RAB9AMEN1KMT2ARGS12 | |
| SCHEMBL5797676 | 0.83 | HDAC6 (0.42) | HDAC6HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL5799057 | 0.82 | HDAC6 (0.52) | HDAC6HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL5797931 | 0.82 | P2RX3 (0.45) | HDAC6HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL5819578 | 0.82 | HDAC6 (0.41) | HDAC6HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL5797935 | 0.82 | P2RX3 (0.45) | HDAC6HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL5818112 | 0.81 | BCHE (0.38) | HDAC6HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL5798801 | 0.80 | HDAC1 (0.38) | HDAC6HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL5797642 | 0.80 | HDAC6 (0.44) | HDAC6HDAC8HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |