Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799654 | 0.90 | NPC1 (0.39) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5796337 | 0.89 | HDAC6 (0.38) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5823657 | 0.84 | ALDH1A1 (0.46) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5819413 | 0.83 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5799028 | 0.82 | MAPT (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5796348 | 0.81 | MEN1 (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5795637 | 0.80 | HDAC1 (0.37) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5799063 | 0.80 | RAB9A (0.48) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5796946 | 0.79 | MTNR1A (0.43) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5796715 | 0.78 | MAPT (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |