Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796804 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5807010 | 0.90 | HDAC6 (0.52) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5807013 | 0.90 | HDAC6 (0.52) | MAPTKDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5824029 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5809477 | 0.84 | MAPK1 (0.41) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5819413 | 0.83 | NPC1 (0.41) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5796113 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5807771 | 0.81 | GCGR (0.46) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5796112 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5810269 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |