Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5796113 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5824029 | 0.94 | ALDH1A1 (0.45) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5822007 | 0.92 | PIN1 (0.44) | ALDH1A1HPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL5807771 | 0.91 | GCGR (0.46) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5807764 | 0.91 | GCGR (0.46) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5810275 | 0.89 | ALDH1A1 (0.43) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5810269 | 0.89 | ALDH1A1 (0.43) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5807110 | 0.89 | P2RX3 (0.49) | ALDH1A1HPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL5807117 | 0.89 | P2RX3 (0.49) | ALDH1A1HPGDSMN1; SMN2MAPTKMT2A | |
| SCHEMBL5797682 | 0.85 | GCGR (0.46) | ALDH1A1HPGDRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |