Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 11/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243686 | 0.77 | GAA (0.54) | CRBNDDB1MEN1KMT2ADUT | |
| SCHEMBL5796877 | 0.74 | CRBN (0.49) | CRBNDDB1DUTGAAPOLB | |
| SCHEMBL5801201 | 0.72 | CRBN (0.46) | CRBNDDB1DUTGAAPOLB | |
| SCHEMBL3993881 | 0.71 | CRBN (0.45) | CRBNDDB1DUTGAAPOLB | |
| SCHEMBL2719765 | 0.65 | CRBN (0.54) | CRBNDDB1DUTPOLBHSD17B10 | |
| SCHEMBL10642564 | 0.65 | CRBN (0.48) | CRBNDDB1DUTPOLBHSD17B10 | |
| SCHEMBL4767721 | 0.64 | CRBN (0.47) | CRBNDDB1DUTGAAPKM | |
| SCHEMBL28377970 | 0.64 | KDM4E (0.43) | MEN1KMT2AGAAPOLBPKM | |
| SCHEMBL725455 | 0.64 | CRBN (0.43) | CRBNDDB1DUTPOLBHSD17B10 | |
| SCHEMBL2787886 | 0.64 | CRBN (0.43) | CRBNDDB1DUTPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |