SCHEMBL3993881

SCHEMBL3993881

C=CC(c1ccccc1)n1ccc(=O)[nH]c1=O

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 3/20 0.45
▸ DDB1 Q16531 1/20 0.45
▸ DUT P33316 11/20 0.41
▸ GAA P10253 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ MET P08581 2/20 0.35
▸ CYP17A1 P05093 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5801201 0.86 CRBN (0.46) CRBNDDB1DUTGAAPOLB
SCHEMBL3629431 0.79 CYP17A1 (0.36) GAAHSD17B10METCYP17A1
SCHEMBL17243686 0.78 GAA (0.54) CRBNDDB1DUTGAAPOLB
SCHEMBL5796877 0.76 CRBN (0.49) CRBNDDB1DUTGAAPOLB
SCHEMBL3993851 0.75 MET (0.45) GAAMET
SCHEMBL264019 0.73 CRBN (0.46) CRBNDDB1DUTPOLBHSD17B10
SCHEMBL5797006 0.71 CRBN (0.44) CRBNDDB1DUTGAAPOLB
SCHEMBL17205220 0.70 CRBN (0.38) CRBNDDB1POLBHSD17B10
SCHEMBL669511 0.70 CRBN (0.42) CRBNDDB1DUTPOLBHSD17B10
SCHEMBL399971 0.69 DUT (0.47) CRBNDDB1DUTPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150290588-A1 SIGNAL RESPONSIVE SOLUTES MCGINNIS ROBERT (US) 2015-10-15 — — US claimed
EP-2928586-A1 SIGNAL RESPONSIVE SOLUTES McGinnis, Robert (US) 2015-10-14 — — EP claimed
WO-2014089142-A1 SIGNAL RESPONSIVE SOLUTES MCGINNIS ROBERT (US) 2014-06-12 — — WO claimed
US-7550136-B2 Photo-reactive polymers and devices for use in hair treatments UNIVERSITY OF MASSACHUSETTS (US) 2009-06-23 — — US claimed
EP-1575537-A4 PHOTO-REACTIVE POLYMERS AND DEVICES FOR USE IN HAIR TREATMENTS UNIV MASSACHUSETTS (US) 2009-02-18 — — EP claimed
EP-1575537-A2 PHOTO-REACTIVE POLYMERS AND DEVICES FOR USE IN HAIR TREATMENTS University of Massachusetts (US) 2005-09-21 — — EP claimed
US-20040206368-A1 Photo-reactive polymers and devices for use in hair treatments UNIVERSITY OF MASSACHUSETTS 2004-10-21 — — US claimed
WO-2004058187-A2 PHOTO-REACTIVE POLYMERS AND DEVICES FOR USE IN HAIR TREATMENTS UNIVERSITY OF MASSACHUSETTS (US) 2004-07-15 — — WO claimed
US-20150321149-A1 SELECTIVE MEMBRANES FORMED BY ALIGNMENT OF POROUS MATERIALS NAGARE MEMBRANES, LLC 2015-11-12 — — US disclosed
US-20150290588-A1 SIGNAL RESPONSIVE SOLUTES MCGINNIS ROBERT (US) 2015-10-15 — — US disclosed
EP-2928586-A1 SIGNAL RESPONSIVE SOLUTES McGinnis, Robert (US) 2015-10-14 — — EP disclosed
WO-2014100412-A1 SELECTIVE MEMBRANES FORMED BY ALIGNMENT OF POROUS MATERIALS MCGINNIS ROBERT (US) 2014-06-26 — — WO disclosed
WO-2014089142-A1 SIGNAL RESPONSIVE SOLUTES MCGINNIS ROBERT (US) 2014-06-12 — — WO disclosed
US-7550136-B2 Photo-reactive polymers and devices for use in hair treatments UNIVERSITY OF MASSACHUSETTS (US) 2009-06-23 — — US disclosed
US-5708106-A PHOTOCROSSLINKED POLAROID CORPORATION (US) 1998-01-13 — — US disclosed
US-5616451-A IMAGES BY EXPOSURE TO ACTINIC RADIATION; SOLVENT REMOVAL OF NON-EXPOSED AREAS POLAROID CORPORATION (US) 1997-04-01 — — US disclosed
EP-0759193-A1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORPORATION (US) 1997-02-26 — — EP disclosed
WO-1995031755-A1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORPORATION (US) 1995-11-23 — — WO disclosed
US-5455349-A For polymers useful in photoresists, imaging POLAROID CORPORATION (US) 1995-10-03 — — US disclosed
US-5395731-A Pendant quaternary ammonium and thymine or uracil groups, diffusion transfer POLAROID CORPORATION (US) 1995-03-07 — — US disclosed
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