Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5553843 | 0.91 | LMNA (0.38) | APPELANESLC6A2CHRNB2CHRNB4 | |
| SCHEMBL5801105 | 0.90 | CNR1 (0.36) | CNR1CNR2ELANEPOLBSMN1; SMN2 | |
| SCHEMBL5801111 | 0.90 | CNR1 (0.36) | CNR1CNR2ELANEPOLBSMN1; SMN2 | |
| SCHEMBL5798158 | 0.90 | ELANE (0.41) | CNR1CNR2ELANEPOLBSMN1; SMN2 | |
| SCHEMBL5561064 | 0.89 | AKR1C3 (0.39) | APPAKR1C3AKR1C2PTGS2 | |
| SCHEMBL5808521 | 0.88 | APP (0.37) | APPAKR1C3AKR1C2PTGS2 | |
| SCHEMBL5824143 | 0.88 | APP (0.38) | APPSLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL5554699 | 0.88 | PTGS2 (0.41) | CNR1CNR2POLBALDH1A1AKR1C3 | |
| SCHEMBL5550614 | 0.88 | PTGS2 (0.41) | CNR1CNR2POLBALDH1A1AKR1C3 | |
| SCHEMBL5553556 | 0.88 | PTGS2 (0.41) | CNR1CNR2POLBALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |