SCHEMBL5797232

SCHEMBL5797232

CC(CO)Oc1ccc(C(C)(C)c2ccc(OC(C)CO)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.47
HTT P42858 2/20 0.41
HIF1A Q16665 2/20 0.41
HPGD P15428 3/20 0.40
TSHR P16473 3/20 0.40
ESR1 P03372 2/20 0.40
CYP3A4 P08684 2/20 0.40
ESR2 Q92731 2/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
HTR6 P50406 1/20 0.40
ESRRG P62508 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
GAA P10253 1/20 0.40
ALDH1A1 P00352 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18069674 0.90 AR (0.41) ARHTTHIF1AHPGDTSHR
SCHEMBL15892043 0.90 AR (0.48) ARHTTHIF1AHPGDTSHR
SCHEMBL18556268 0.89 SMN1; SMN2 (0.53) ARHTTHIF1AHPGDTSHR
SCHEMBL11598153 0.89 NR1H4 (0.47) HPGDHSD17B10MEN1KMT2ASMN1; SMN2
SCHEMBL10627656 0.88 AR (0.46) ARHTTHIF1AHPGDTSHR
SCHEMBL12190272 0.87 AR (0.56) ARHTTHIF1AHPGDTSHR
SCHEMBL10629565 0.87 AR (0.44) ARHTTHIF1AHPGDTSHR
SCHEMBL10629728 0.85 MTNR1A (0.44) TSHRKMT2AGAACYP1A2MTNR1A
SCHEMBL18687007 0.85 AR (0.50) ARHTTHIF1AHPGDTSHR
SCHEMBL7018753 0.83 PPARG (0.45) HTTHPGDTSHRCYP3A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493077-B1 Mouldable polyester resin having high melting heat stability and moulded article produced therefrom POLYPLASTICS CO (JP) 1997-04-02 EP claimed
US-5182359-A Sheets and films having good surface gloss POLYPLASTICS CO., LTD. (JP) 1993-01-26 US claimed
EP-0493077-A2 Mouldable polyester resin having high melting heat stability and moulded article produced therefrom POLYPLASTICS CO. LTD. (JP) 1992-07-01 EP claimed
US-9822218-B2 Process for producing a high molecular-weight aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-11-21 US disclosed
US-9822218-B2 Process for producing a high molecular-weight aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-11-21 US disclosed
EP-2674445-B1 PROCESS FOR MANUFACTURING BRANCHED AROMATIC POLYCARBONATE RESIN WITH DESIRED DEGREE OF BRANCHING MITSUBISHI GAS CHEMICAL CO (JP) 2017-10-11 EP disclosed
US-9701788-B2 Method for producing branched aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-07-11 US disclosed
US-9701788-B2 Method for producing branched aromatic polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-07-11 US disclosed
US-20170174833-A1 HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-06-22 US disclosed
US-20170174833-A1 HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-06-22 US disclosed
US-20160272757-A1 PROCESS FOR PRODUCING A HIGH MOLECULAR-WEIGHT AROMATIC POLYCARBONATE RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-22 US disclosed
US-20100159376-A1 TONERS CONTAINING POLYHEDRAL OLIGOMERIC SILSESQUIOXANES XEROX CORPORATION (US) 2010-06-24 US disclosed
US-20100159376-A1 TONERS CONTAINING POLYHEDRAL OLIGOMERIC SILSESQUIOXANES XEROX CORPORATION (US) 2010-06-24 US disclosed
WO-2006046733-A1 THIOL COMPOUND, AND PHOTOSENSITIVE COMPOSITION AND BLACK MATRIX RESIST COMPOSITION USING THE COMPOUND SHOWA DENKO K.K (JP) 2006-05-04 WO disclosed
EP-0493077-B1 Mouldable polyester resin having high melting heat stability and moulded article produced therefrom POLYPLASTICS CO (JP) 1997-04-02 EP disclosed
US-5233016-A Copolyesters from monomers including cis- and trans-stereoisomers of 1,4-cyclohexanedimethanol; improved thermal stability and processability POLYPLASTICS CO., LTD. (JP) 1993-08-03 US disclosed
US-5182359-A Sheets and films having good surface gloss POLYPLASTICS CO., LTD. (JP) 1993-01-26 US disclosed
EP-0493077-A2 Mouldable polyester resin having high melting heat stability and moulded article produced therefrom POLYPLASTICS CO. LTD. (JP) 1992-07-01 EP disclosed
US-4790907-A Synthetic fiber INTERA COMPANY, LTD. (US) 1988-12-13 US disclosed
US-4726968-A EMULSION POLYMERIZATION OF WATER-SOLUBLE CROSSLINKING VINYL MONOMER INTERA COMPANY, LTD., A TENNESSEE LIMITED PARTNERSHIP (US) 1988-02-23 US disclosed