Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797304 | 1.00 | ELANE (0.41) | ELANESMN1; SMN2CNR1CNR2MGLL | |
| SCHEMBL5797205 | 0.94 | ELANE (0.38) | ELANESMN1; SMN2CNR1CNR2MGLL | |
| SCHEMBL5797209 | 0.94 | ELANE (0.38) | ELANESMN1; SMN2CNR1CNR2MGLL | |
| SCHEMBL5801301 | 0.92 | PTGS2 (0.38) | ELANESMN1; SMN2CNR1CNR2KMT2A | |
| SCHEMBL5801297 | 0.92 | PTGS2 (0.38) | ELANESMN1; SMN2CNR1CNR2KMT2A | |
| SCHEMBL5560746 | 0.91 | ELANE (0.37) | ELANESMN1; SMN2CNR1CNR2MGLL | |
| SCHEMBL5813474 | 0.91 | ELANE (0.35) | ELANESMN1; SMN2CNR1CNR2L3MBTL1 | |
| SCHEMBL5813477 | 0.91 | ELANE (0.35) | ELANESMN1; SMN2CNR1CNR2L3MBTL1 | |
| SCHEMBL5797274 | 0.89 | PTGS2 (0.42) | — | |
| SCHEMBL5797277 | 0.89 | PTGS2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |