Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797209 | 1.00 | ELANE (0.38) | ELANECNR1CNR2PTGS2SMN1; SMN2 | |
| SCHEMBL5801301 | 0.95 | PTGS2 (0.38) | ELANECNR1CNR2PTGS2SMN1; SMN2 | |
| SCHEMBL5801297 | 0.95 | PTGS2 (0.38) | ELANECNR1CNR2PTGS2SMN1; SMN2 | |
| SCHEMBL5797308 | 0.94 | ELANE (0.41) | ELANECNR1CNR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5797304 | 0.94 | ELANE (0.41) | ELANECNR1CNR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL5800661 | 0.90 | PTGS2 (0.37) | PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL5798592 | 0.90 | PTGS2 (0.44) | PTGS2 | |
| SCHEMBL5800660 | 0.90 | PTGS2 (0.37) | PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL5798596 | 0.90 | PTGS2 (0.44) | PTGS2 | |
| SCHEMBL5797617 | 0.89 | CNR1 (0.38) | ELANECNR1CNR2PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |