Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799702 | 0.88 | ESR1 (0.43) | MAPTCDC25BALDH1A1NPSR1NPC1 | |
| SCHEMBL5797413 | 0.88 | HDAC6 (0.51) | MAPTMCL1CDC25BTDP1ALDH1A1 | |
| SCHEMBL5797237 | 0.86 | MAPT (0.63) | MAPTMCL1TDP1ALDH1A1POLB | |
| SCHEMBL5799686 | 0.81 | MEN1 (0.50) | MAPTMCL1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL5795676 | 0.81 | MAPT (0.51) | MAPTMCL1TDP1ALDH1A1POLB | |
| SCHEMBL5799662 | 0.75 | HDAC6 (0.48) | MAPTMCL1TDP1POLBL3MBTL1 | |
| SCHEMBL5798829 | 0.75 | HDAC6 (0.57) | MAPTMCL1TDP1ALDH1A1NPSR1 | |
| SCHEMBL5795739 | 0.75 | NPC1 (0.43) | MAPTTDP1ALDH1A1POLBGLA | |
| SCHEMBL5796792 | 0.75 | MAPT (0.49) | MAPTMCL1TDP1ALDH1A1NPSR1 | |
| SCHEMBL5807460 | 0.74 | GAA (0.45) | MAPTTDP1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |