Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795676 | 0.89 | MAPT (0.51) | MAPTMCL1KMT2AMEN1KDM4E | |
| SCHEMBL5798829 | 0.88 | HDAC6 (0.57) | MAPTMCL1KMT2AMEN1KDM4E | |
| SCHEMBL5796792 | 0.88 | MAPT (0.49) | MAPTMCL1KMT2AMEN1KDM4E | |
| SCHEMBL5797556 | 0.86 | MAPT (0.47) | MAPTMCL1KMT2AMEN1KDM4E | |
| SCHEMBL5799686 | 0.82 | MEN1 (0.50) | MAPTMCL1KMT2AMEN1KDM4E | |
| SCHEMBL5799662 | 0.81 | HDAC6 (0.48) | MAPTMCL1KMT2AKDM4ETDP1 | |
| SCHEMBL5812089 | 0.78 | HDAC6 (0.57) | MAPTMCL1KMT2AMEN1KDM4E | |
| SCHEMBL5799477 | 0.78 | HDAC3 (0.42) | MAPTMCL1KMT2AMEN1KDM4E | |
| SCHEMBL5799558 | 0.78 | ALDH1A1 (0.63) | MAPTKMT2AMEN1KDM4ETDP1 | |
| SCHEMBL5795739 | 0.76 | NPC1 (0.43) | MAPTKMT2AMEN1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |