Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797556 | 0.88 | MAPT (0.47) | CDC25BALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5796792 | 0.87 | MAPT (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL5797413 | 0.86 | HDAC6 (0.51) | CDC25BALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5799162 | 0.82 | MEN1 (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL5799477 | 0.82 | HDAC3 (0.42) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL5798915 | 0.76 | SLC40A1 (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL5797068 | 0.76 | NPC1 (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL5799119 | 0.75 | RAB9A (0.58) | ALOX5ALDH1A1PTPN1SMN1; SMN2RAB9A | |
| SCHEMBL5797237 | 0.75 | MAPT (0.63) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL5798829 | 0.73 | HDAC6 (0.57) | ALDH1A1RAB9ANPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |