Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968167 | 0.86 | ALDH1A1 (0.41) | MIFCYP19A1LMNAALDH1A1TSHR | |
| SCHEMBL4199249 | 0.75 | ALDH1A1 (0.58) | LMNAALDH1A1TSHRNPSR1HPGD | |
| SCHEMBL4203695 | 0.66 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDMAPTMAPK1 | |
| SCHEMBL4208917 | 0.65 | MMP3 (0.42) | CYP19A1LMNAALDH1A1TSHRCYP3A4 | |
| SCHEMBL27859073 | 0.61 | TYR (0.58) | CYP19A1RAB9A | |
| SCHEMBL28703154 | 0.61 | TYR (0.58) | CYP19A1RAB9A | |
| SCHEMBL14545540 | 0.61 | STS (0.56) | MIFLMNAALDH1A1TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL27841331 | 0.60 | TYR (0.57) | MIFCYP19A1RAB9A | |
| SCHEMBL31086452 | 0.60 | ALDH1A1 (0.44) | MIFLMNAALDH1A1TSHRHPGD | |
| SCHEMBL13086831 | 0.60 | CYP19A1 (0.46) | MIFCYP19A1LMNAALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615637-A1 | PHARMACEUTICAL USE OF SUBSTITUTED 1,2,4-TRIAZOLES | NOVO NORDISK A/S (DK) | 2006-01-18 | — | — | EP | claimed |
| WO-2004089367-A1 | PHARMACEUTICAL USE OF SUBSTITUTED 1,2,4-TRIAZOLES | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | claimed |