Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14334375 | 0.94 | LTA4H (0.51) | LTA4HMEN1KMT2APOLBLMNA | |
| SCHEMBL7001657 | 0.80 | MEN1 (0.51) | MEN1KMT2APOLBALDH1A1NPC1 | |
| SCHEMBL14376687 | 0.77 | LTA4H (0.64) | LTA4HMEN1KMT2APOLBCYP1A2 | |
| SCHEMBL620836 | 0.75 | MEN1 (0.52) | LTA4HMEN1KMT2APOLBCYP1A2 | |
| SCHEMBL14334243 | 0.74 | MEN1 (0.44) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL14334762 | 0.73 | LTA4H (0.57) | LTA4HMEN1KMT2APOLBCYP1A2 | |
| SCHEMBL12519500 | 0.72 | POLB (0.63) | LTA4HMEN1KMT2APOLBLMNA | |
| SCHEMBL2368431 | 0.72 | ALDH1A1 (0.56) | LTA4HMEN1KMT2APOLBLMNA | |
| SCHEMBL31701918 | 0.72 | ALDH1A1 (0.60) | LTA4HMEN1KMT2APOLBLMNA | |
| SCHEMBL19172851 | 0.72 | ALDH1A1 (0.56) | LTA4HMEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025717-A1 | PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |