Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708298 | 0.83 | TSHR (0.54) | TSHRMAPK1TLR7PDE10ARECQL | |
| SCHEMBL4320463 | 0.82 | TLR7 (0.50) | TSHRMAPK1TLR7PDE10ARECQL | |
| SCHEMBL4317408 | 0.81 | TLR7 (0.52) | TSHRMAPK1TLR7PDE10ARECQL | |
| SCHEMBL5354699 | 0.81 | TLR7 (0.47) | TSHRMAPK1TLR7PDE10ARECQL | |
| SCHEMBL27708265 | 0.80 | TSHR (0.47) | TSHRMAPK1TLR7PDE10ARECQL | |
| SCHEMBL5635079 | 0.79 | TSHR (0.44) | TSHRMAPK1TLR7PDE10ARECQL | |
| SCHEMBL20796976 | 0.78 | TLR7 (0.46) | TSHRTLR7PDE10ARECQLMEN1 | |
| SCHEMBL8565615 | 0.78 | TSHR (0.47) | TSHRMAPK1TLR7PDE10ARECQL | |
| SCHEMBL1036042 | 0.77 | TLR7 (0.53) | TSHRMAPK1TLR7PDE10ARECQL | |
| SCHEMBL5349584 | 0.77 | TLR7 (0.52) | TSHRMAPK1TLR7PDE10ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699788-A2 | IMIDAZOQUINOLINYL, IMIDAZOPYRIDINYL AND IMIDAZONAPHTHYRIDINYL SULFONAMIDES | 3M Innovative Properties Company (US) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005066169-A2 | IMIDAZOQUINOLINYL, IMIDAZOPYRIDINYL, AND IMIDAZONAPHTHYRIDINYL SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |