Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589469 | 0.89 | TLR7 (0.52) | TSHRNPSR1TLR7LMNAPOLB | |
| SCHEMBL1490771 | 0.88 | LMNA (0.43) | TSHRNPSR1TLR7LMNAPOLB | |
| SCHEMBL6719567 | 0.88 | TLR7 (0.43) | TSHRMAPK1NPSR1TLR7LMNA | |
| SCHEMBL6722232 | 0.86 | TLR7 (0.50) | TSHRNPSR1TLR7LMNAPOLB | |
| SCHEMBL6723871 | 0.86 | TLR7 (0.52) | TSHRNPSR1TLR7LMNAPOLB | |
| SCHEMBL6719536 | 0.86 | L3MBTL1 (0.42) | TSHRNPSR1TLR7LMNAPOLB | |
| SCHEMBL6726435 | 0.85 | LMNA (0.42) | TSHRNPSR1TLR7LMNAPOLB | |
| SCHEMBL6724102 | 0.84 | TLR7 (0.40) | TSHRNPSR1TLR7LMNAPOLB | |
| SCHEMBL6719520 | 0.84 | TLR7 (0.42) | TSHRNPSR1TLR7LMNAPOLB | |
| SCHEMBL6724014 | 0.83 | SMN1; SMN2 (0.47) | TSHRNPSR1TLR7LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641342-B1 | ANTIVIRAL 2-ETHYL-1H-IMIDAZO(4,5-C)QUINOLIN-4-AMINES | MINNESOTA MINING & MFG (US) | 1998-08-05 | — | — | EP | disclosed |
| EP-0641342-A1 | ANTIVIRAL 2-ETHYL-1H-IMIDAZO(4,5-C)QUINOLIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5266575-A | Immunomodulator, viricides | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-11-30 | — | — | US | disclosed |
| WO-1993009119-A1 | ANTIVIRAL 2-ETHYL-1H-IMIDAZO(4,5-C)QUINOLIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |