Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20305297 | 0.86 | ALDH1A1 (0.54) | CA9CA1CA12CA4CA2 | |
| SCHEMBL5704167 | 0.86 | CA12 (0.63) | CA9CA1CA12CA4CA2 | |
| SCHEMBL8034410 | 0.86 | MAOB (0.46) | CA9CA1CA12CA4CA2 | |
| Hydrochloric Acid SCHEMBL21694040 | 0.84 | CA12 (0.61) | CA9CA1CA12CA4CA2 | |
| SCHEMBL6574222 | 0.82 | MAOB (0.53) | CA9CA1CA12CA2MAOB | |
| SCHEMBL9155218 | 0.79 | GSTP1 (0.68) | CA9CA1CA12CA4CA2 | |
| SCHEMBL15800551 | 0.79 | CA12 (0.57) | CA9CA1CA12CA4CA2 | |
| SCHEMBL31725708 | 0.79 | MAOB (0.49) | CA9CA1CA12CA4CA2 | |
| SCHEMBL5981836 | 0.79 | MAOB (0.49) | CA9CA1CA12CA4CA2 | |
| SCHEMBL14922474 | 0.78 | MAOB (0.50) | CA9CA1CA12CA2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220117231-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | BASF SE (DE) | 2022-04-21 | — | — | US | disclosed |
| US-10889546-B2 | Alkynyl pyridine prolyl hydroxylase inhibitor, and preparation method and medical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2021-01-12 | — | — | US | disclosed |
| US-20200407319-A1 | ALKYNYL PYRIDINE PROLYL HYDROXYLASE INHIBITOR, AND PREPARATION METHOD AND MEDICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. | 2020-12-31 | — | — | US | disclosed |
| CN-107848976-B | Alkynyl pyridine prolyl hydroxylase inhibitor, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2020-11-17 | — | — | CN | disclosed |
| EP-3360862-B1 | ALKYNYL PYRIDINE PROLYL HYDROXYLASE INHIBITOR, AND PREPARATION METHOD AND MEDICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2020-04-22 | — | — | EP | disclosed |
| CN-109336829-A | Aryl methanamide compounds of the triazole structure containing 1,2,3- and application thereof | 沈阳药科大学 | 2019-02-15 | — | — | CN | disclosed |
| US-20180305317-A1 | ALKYNYL PYRIDINE PROLYL HYDROXYLASE INHIBITOR, AND PREPARATION METHOD AND MEDICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2018-10-25 | — | — | US | disclosed |
| US-9968092-B2 | Combination of novel nitrification inhibitors and biopesticides as well as combination of (thio)phosphoric acid triamides and biopesticides | BASF SE (DE) | 2018-05-15 | — | — | US | disclosed |
| US-9968092-B2 | Combination of novel nitrification inhibitors and biopesticides as well as combination of (thio)phosphoric acid triamides and biopesticides | BASF SE (DE) | 2018-05-15 | — | — | US | disclosed |
| CN-107459491-A | Benzamide compound containing 1,2,3 triazole structures and application thereof | 沈阳药科大学 | 2017-12-12 | — | — | CN | disclosed |
| EP-1569644-A4 | INDOLIZINE COMPOUNDS | SYNTA PHARMACEUTICALS CORP (US) | 2006-08-30 | — | — | EP | disclosed |
| EP-1569644-A2 | INDOLIZINE COMPOUNDS | Synta Pharmaceuticals Corporation (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004054507-A2 | INDOLIZINE COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2004-07-01 | — | — | WO | disclosed |
| US-20030204090-A1 | Indolizine compounds | SYNTA PHARMACEUTICALS CORP. | 2003-10-30 | — | — | US | disclosed |
| EP-1192170-B1 | PROPARGYL PHENYL ETHER A2A RECEPTOR AGONISTS | CV THERAPEUTICS INC (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1192170-A1 | PROPARGYL PHENYL ETHER A2A RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2002-04-03 | — | — | EP | disclosed |
| US-6180615-B1 | STIMULATE MAMMALIAN CORONARY VASODILATATION FOR THERAPEUTIC PURPOSES AND FOR PURPOSES OF IMAGING THE HEART | CV THERAPEUTICS, INC. | 2001-01-30 | — | — | US | disclosed |
| WO-2000078777-A1 | PROPARGYL PHENYL ETHER A2A RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| US-4867915-A | LIPOXYGENASE INHIBITORS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1989-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305317-A1 | ALKYNYL PYRIDINE PROLYL HYDROXYLASE INHIBITOR, AND PREPARATION METHOD AND MEDICAL USE THEREOF | EGLN3, EGLN2, EPOR | CA9 2073/4885CA1 2847/4885CA12 4360/4885 |
| US-20220117231-A1 | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides | NMT2, NAPRT, NAMPT | CA9 894/4885CA1 782/4885CA12 1592/4885 |
| US-10889546-B2 | Alkynyl pyridine prolyl hydroxylase inhibitor, and preparation method and medical use thereof | EGLN3, EGLN2, EPOR | CA9 2073/4885CA1 2847/4885CA12 4360/4885 |
| US-20200407319-A1 | ALKYNYL PYRIDINE PROLYL HYDROXYLASE INHIBITOR, AND PREPARATION METHOD AND MEDICAL USE THEREOF | EGLN3, EGLN2, EPOR | CA9 2073/4885CA1 2847/4885CA12 4360/4885 |
| US-20030204090-A1 | Indolizine compounds | IDO1, IDO2, PDE4A | CA9 703/4885CA1 1254/4885CA12 2197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.