Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.55 |
| ▸ | PPARA | Q07869 | 18/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819389 | 0.87 | PPARG (0.57) | PPARGPPARACYP2C9CYP3A4KCNH2 | |
| SCHEMBL5823378 | 0.80 | PPARG (0.57) | PPARGPPARACYP2C9CYP3A4KCNH2 | |
| SCHEMBL5798755 | 0.79 | PPARA (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5798753 | 0.79 | PPARA (0.51) | PPARGPPARAPPARD | |
| SCHEMBL4283015 | 0.76 | PPARG (0.63) | PPARGPPARACYP2C9CYP3A4KCNH2 | |
| SCHEMBL170065 | 0.76 | PPARG (0.63) | PPARGPPARACYP2C9CYP3A4KCNH2 | |
| SCHEMBL10367689 | 0.76 | PPARG (0.60) | PPARGPPARACYP2C9CYP3A4KCNH2 | |
| SCHEMBL13718953 | 0.75 | PPARA (0.64) | PPARGPPARAPPARD | |
| SCHEMBL4026294 | 0.74 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL12616442 | 0.74 | PPARG (0.84) | PPARGPPARACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006041921-A2 | PREPARATION AND USES OF RHODANINE DERIVATIVES | AUSPEX PHARMACEUTICALS, INC. (US) | 2006-04-20 | — | — | WO | disclosed |