Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905650 | 0.88 | — | — | |
| SCHEMBL1537424 | 0.88 | — | — | |
| SCHEMBL3614516 | 0.88 | — | — | |
| SCHEMBL75611 | 0.82 | HPGD (0.58) | HPGDGAASMN1; SMN2CA12CA1 | |
| SCHEMBL9162112 | 0.82 | HPGD (0.58) | HPGDGAASMN1; SMN2CA12CA1 | |
| SCHEMBL31518814 | 0.82 | HPGD (0.58) | HPGDGAASMN1; SMN2CA12CA1 | |
| SCHEMBL8137653 | 0.81 | DPP4 (0.58) | HPGDDPP4DPP8PREPFAP | |
| Formic Acid SCHEMBL6122296 | 0.81 | HPGD (0.44) | HPGDGAASMN1; SMN2CA12CA1 | |
| SCHEMBL1631843 | 0.81 | DPP4 (0.58) | HPGDDPP4DPP8PREPFAP | |
| Ammonia Solution, Strong SCHEMBL27259881 | 0.80 | HPGD (0.56) | HPGDGAASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060120980-A1 | Novel dermatological composition using bio-activating organocatalysts | EBERSYTES, LLC | 2006-06-08 | — | — | US | disclosed |
| WO-2006060548-A2 | NOVEL DERMATOLOGICAL COMPOSITION USING BIO-ACTIVATING ORGANOCATALYSTS | EBERSYTES, LLC (US) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060120980-A1 | Novel dermatological composition using bio-activating organocatalysts | FGF1, FGF2, FGFR3 | HPGD 1568/4885DPP4 3836/4885DPP8 3355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.