Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.58 |
| ▸ | PREP | P48147 | 2/20 | 0.58 |
| ▸ | FAP | Q12884 | 1/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1631843 | 1.00 | DPP4 (0.58) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL18620645 | 0.94 | HPGD (0.53) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL18793797 | 0.94 | HPGD (0.53) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL1632385 | 0.88 | — | — | |
| SCHEMBL1631030 | 0.85 | CHRM2 (0.46) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL1860910 | 0.82 | SMYD3 (0.43) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL13674784 | 0.82 | HPGD (0.47) | DPP4HPGDSMN1; SMN2GAAKMT2A | |
| SCHEMBL14218669 | 0.82 | HPGD (0.47) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL1632770 | 0.82 | HPGD (0.47) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL14301360 | 0.82 | HPGD (0.47) | DPP4HPGDSMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131149-A2 | CRYSTAL FORMS OF SAXAGLIPTIN AND PROCESSES FOR PREPARING SAME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-10-30 | — | — | WO | disclosed |