Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | TOP2A | P11388 | 6/20 | 0.68 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.68 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | TUBB | P07437 | 1/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.67 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL2781733 | 1.00 | KDM4E (0.70) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL2089512 | 0.98 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL29406062 | 0.98 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL2877827 | 0.98 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL2333806 | 0.98 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL29872315 | 0.98 | KDM4E (0.72) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Water SCHEMBL4394501 | 0.97 | KDM4E (0.71) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| Water SCHEMBL4384786 | 0.97 | KDM4E (0.71) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL2183859 | 0.94 | KDM4E (0.68) | KDM4EKMT2ATOP2ATOP2BALDH1A1 | |
| SCHEMBL5144854 | 0.94 | KDM4E (0.68) | KDM4EKMT2ATOP2ATOP2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670793-A1 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20050070523-A1 | Antibacterial agents | HAGEN SUSAN (US) | 2005-03-31 | — | — | US | disclosed |
| WO-2005026161-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | LABORATORIOS VITA, S.A. (ES) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070523-A1 | Antibacterial agents | MRPL21, ABCB11, NQO1 | KDM4E 4013/4885KMT2A 4755/4885TOP2A 28/4885 |
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | OXA1L, Q6ZSR9, PGC | KDM4E 2554/4885KMT2A 3161/4885TOP2A 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.