Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433980 | 0.80 | NQO2 (1.00) | NQO2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL54737 | 0.79 | KMT2A (0.69) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL31590799 | 0.79 | KMT2A (0.69) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL11512860 | 0.76 | KDM4E (0.57) | NQO2KMT2AMEN1GFERKDM4E | |
| SCHEMBL7747949 | 0.72 | HDAC3 (0.72) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2007035 | 0.71 | MEN1 (0.76) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL28046011 | 0.70 | ALDH1A1 (0.55) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| Edulitine SCHEMBL3188973 | 0.69 | NQO2 (0.76) | NQO2KMT2AMEN1MAPTKDM4E | |
| Edulitine SCHEMBL30631639 | 0.69 | NQO2 (0.76) | NQO2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL26607693 | 0.69 | NQO2 (0.70) | NQO2KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706384-A1 | THERAPEUTIC AGENTS I | AstraZeneca AB (SE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005066132-A1 | THERAPEUTIC AGENTS I | ASTRAZENECA AB (SE) | 2005-07-21 | — | — | WO | disclosed |