Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820041 | 0.92 | PTGS2 (0.42) | PTGS2PTGS1CYP19A1GAA | |
| SCHEMBL6426829 | 0.91 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL6423291 | 0.91 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5800397 | 0.91 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5822808 | 0.90 | PTGS2 (0.40) | PTGS2PTGS1 | |
| SCHEMBL6423267 | 0.89 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6425513 | 0.89 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL5797224 | 0.89 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL5797942 | 0.88 | PTGS2 (0.43) | PTGS2PTGS1CYP19A1 | |
| SCHEMBL5554435 | 0.86 | PTGS2 (0.38) | PTGS2TSHRCYP19A1HPGDHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050120-A2 | SYNTHESIS OF COX-2 AND FAAH INHIBITORS | MICROBIA, INC. (US) | 2006-05-11 | — | — | WO | disclosed |