Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | TTPA | P49638 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597029 | 0.72 | PTGS1 (0.54) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL18263520 | 0.71 | PTGS1 (0.40) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL4274823 | 0.69 | PTGS1 (0.47) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL4278705 | 0.68 | PTGS1 (0.48) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL3660430 | 0.67 | PTGS1 (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL4283972 | 0.66 | PTGS1 (0.46) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL31326009 | 0.64 | PTGS1 (0.40) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL31326003 | 0.64 | PTGS1 (0.40) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL245304 | 0.63 | ALDH1A1 (0.47) | TSHRALDH1A1THRBCA1CA2 | |
| SCHEMBL20505422 | 0.62 | ALDH1A1 (0.68) | CYP3A4TSHRALDH1A1THRBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006058326-A2 | STABILIZATION OF ANTIOXIDANTS | UNIVERSITY OF PITTSBURGH (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20060116451-A1 | Stabilization of antioxidants | UNIVERSITY OF PITTSBURGH | 2006-06-01 | — | — | US | disclosed |