Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25574251 | 0.85 | ALDH1A1 (0.45) | BACE1ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL29041518 | 0.82 | LMNA (0.52) | ALDH1A1LMNATSHRKDM4EHSD17B10 | |
| SCHEMBL28658058 | 0.79 | BACE1 (0.56) | BACE1ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL12678685 | 0.79 | BACE1 (0.56) | BACE1ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL5798938 | 0.77 | ALDH1A1 (0.47) | BACE1ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL30041782 | 0.76 | LMNA (0.46) | ALDH1A1LMNATSHRKDM4EHSD17B10 | |
| SCHEMBL5839700 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL436238 | 0.76 | LMNA (0.46) | ALDH1A1LMNATSHRKDM4EHSD17B10 | |
| SCHEMBL3540201 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL17424944 | 0.76 | LMNA (0.59) | ALDH1A1LMNATSHRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | claimed |