Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798873 | 0.86 | PARP14 (0.41) | KMT2AMEN1ATMPARP14SMN1; SMN2 | |
| SCHEMBL5797058 | 0.86 | PARP14 (0.43) | KMT2AMEN1ATMPARP14SMN1; SMN2 | |
| SCHEMBL5799313 | 0.84 | KMT2A (0.38) | KMT2AMEN1ATMPARP14SMN1; SMN2 | |
| SCHEMBL5796179 | 0.82 | MEN1 (0.39) | KMT2AMEN1ATMPARP14SMN1; SMN2 | |
| SCHEMBL5798884 | 0.80 | PARP14 (0.37) | KMT2AMEN1PARP14SMN1; SMN2MAPT | |
| SCHEMBL5798816 | 0.79 | MAPT (0.43) | KMT2AMEN1ATMPARP14MAPT | |
| SCHEMBL5798821 | 0.79 | MAPT (0.43) | KMT2AMEN1ATMPARP14MAPT | |
| SCHEMBL5798774 | 0.79 | PARP14 (0.43) | KMT2AMEN1PARP14SMN1; SMN2MAPT | |
| SCHEMBL5824180 | 0.79 | HDAC6 (0.40) | KMT2AMEN1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL5799274 | 0.78 | HDAC1 (0.49) | KMT2AMEN1PARP14HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |