Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5799054 | 0.94 | FLT3 (0.38) | KMT2AMEN1ATMHDAC1NPC1 | |
| SCHEMBL5795517 | 0.92 | P2RX3 (0.42) | HDAC1NPC1RAB9AP2RX3PARP14 | |
| SCHEMBL5795513 | 0.92 | P2RX3 (0.42) | HDAC1NPC1RAB9AP2RX3PARP14 | |
| SCHEMBL5797058 | 0.89 | PARP14 (0.43) | KMT2AMEN1ATMHDAC1RAB9A | |
| SCHEMBL5798873 | 0.88 | PARP14 (0.41) | KMT2AMEN1ATMHDAC1NPC1 | |
| SCHEMBL5798884 | 0.87 | PARP14 (0.37) | KMT2AMEN1NPC1RAB9ATDO2 | |
| SCHEMBL5824180 | 0.84 | HDAC6 (0.40) | KMT2AMEN1HDAC1NPC1RAB9A | |
| SCHEMBL5799100 | 0.84 | KMT2A (0.39) | KMT2AMEN1ATMHDAC1P2RX3 | |
| SCHEMBL5798774 | 0.83 | PARP14 (0.43) | KMT2AMEN1HDAC1NPC1RAB9A | |
| SCHEMBL5813698 | 0.82 | NOTUM (0.39) | KMT2AMEN1ATMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |